Pesquisa sobre: DNA TOPOISOMERASE IV 
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Descritor Inglês:   DNA Topoisomerase IV 
Descritor Espanhol:   Topoisomerasa de ADN IV 
Descritor Português:   DNA Topoisomerase IV 
Sinônimos Inglês:   parC Protein
parE Protein  
Categoria:   D08.811.399.403.741.224
D12.776.097.256
Definição Inglês:   A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. 
Nota Histórica Inglês:   2002; use DNA TOPOISOMERASE IV (NM) 1991-2001 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   36090 
Identificador Único:   D027101 

Ocorrência na BVS:
 

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